CARRASCO PÁEZ, Luis et al. Proteínas de estrés: respuestas y funciones de HSP70 en el músculo esquelético durante el ejercicio físico. Revista Andaluza de Medicina del Deporte, Sevilla, v. 2, n. 4, p. 141-148, dic. 2009.
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Among the various mechanisms that the body has to counteract the disruption of homeostasis, one of the most important is the production of stress proteins or heat shock proteins (HSP). Thus, in the skeletal muscle, the family of HSP70 serves as protection against oxidative stress, reduces muscle weakening during immobilization and enhances muscle regeneration, attenuating muscle damage. Factors such as age, sex, training level, intensity and volume of exercise performed or even the type of muscle fi ber, appear to determine HSP70 responses, whose functions during exercise are also related with energetic metabolism regulation. However, due to lack of consistent results or existing disputes, further studies are needed in order to more accurately defi ne the biological function of HSP70 related with physical exercise. |
